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human ccrcc cell line a498  (ATCC)


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    ATCC human ccrcc cell line a498
    Human Ccrcc Cell Line A498, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1667 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+ccrcc+cell+line+a498/A-498/pm41972721-61-1-6
    Average 97 stars, based on 1667 article reviews
    human ccrcc cell line a498 - by Bioz Stars, 2026-09
    97/100 stars

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    human ccrcc cell line a498  (ATCC)
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    ATCC human ccrcc cell line a498
    Human Ccrcc Cell Line A498, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    FIGURE 2 mRNA and protein expression levels of LAMP1 in <t>ccRCC</t> and ROC curve analysis (A) LAMP1 mRNA expression levels in ccRCC tissues (n=539) and normal tissues (n=72); (B) LAMP1 mRNA expression levels in ccRCC tissues (n=72) and its paired tissues (n=72); (C) LAMP1 protein expression level in UNCLAN database; (D) ROC curve to assess the differentiation of LAMP1 between tumor and normal tissue (***P<0.001).
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    FIGURE 2 mRNA and protein expression levels of LAMP1 in <t>ccRCC</t> and ROC curve analysis (A) LAMP1 mRNA expression levels in ccRCC tissues (n=539) and normal tissues (n=72); (B) LAMP1 mRNA expression levels in ccRCC tissues (n=72) and its paired tissues (n=72); (C) LAMP1 protein expression level in UNCLAN database; (D) ROC curve to assess the differentiation of LAMP1 between tumor and normal tissue (***P<0.001).
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    cell lines human ccrcc cell lines a498  (ATCC)
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    ATCC cell lines human ccrcc cell lines a498
    FIGURE 2 mRNA and protein expression levels of LAMP1 in <t>ccRCC</t> and ROC curve analysis (A) LAMP1 mRNA expression levels in ccRCC tissues (n=539) and normal tissues (n=72); (B) LAMP1 mRNA expression levels in ccRCC tissues (n=72) and its paired tissues (n=72); (C) LAMP1 protein expression level in UNCLAN database; (D) ROC curve to assess the differentiation of LAMP1 between tumor and normal tissue (***P<0.001).
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    Average 97 stars, based on 1 article reviews
    cell lines human ccrcc cell lines a498 - by Bioz Stars, 2026-09
    97/100 stars
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    FIGURE 2 mRNA and protein expression levels of LAMP1 in ccRCC and ROC curve analysis (A) LAMP1 mRNA expression levels in ccRCC tissues (n=539) and normal tissues (n=72); (B) LAMP1 mRNA expression levels in ccRCC tissues (n=72) and its paired tissues (n=72); (C) LAMP1 protein expression level in UNCLAN database; (D) ROC curve to assess the differentiation of LAMP1 between tumor and normal tissue (***P<0.001).

    Journal: Frontiers in immunology

    Article Title: Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.

    doi: 10.3389/fimmu.2024.1494005

    Figure Lengend Snippet: FIGURE 2 mRNA and protein expression levels of LAMP1 in ccRCC and ROC curve analysis (A) LAMP1 mRNA expression levels in ccRCC tissues (n=539) and normal tissues (n=72); (B) LAMP1 mRNA expression levels in ccRCC tissues (n=72) and its paired tissues (n=72); (C) LAMP1 protein expression level in UNCLAN database; (D) ROC curve to assess the differentiation of LAMP1 between tumor and normal tissue (***P<0.001).

    Article Snippet: The human ccRCC cell lines A498 and 786-O were obtained from ATCC (Manassas, VA, USA).

    Techniques: Expressing

    FIGURE 3 The relationship between LAMP1 expression level and patients’ prognosis and survival. (A-C) low LAMP1 expression was associated with worse OS, DSS, and PFI in patients. (D-I) OS survival curve of ccRCC patients with T3&4, T3, M1, G3&4, Stage III&IV, and Stage IV subgroups in LAMP1 high and low groups.

    Journal: Frontiers in immunology

    Article Title: Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.

    doi: 10.3389/fimmu.2024.1494005

    Figure Lengend Snippet: FIGURE 3 The relationship between LAMP1 expression level and patients’ prognosis and survival. (A-C) low LAMP1 expression was associated with worse OS, DSS, and PFI in patients. (D-I) OS survival curve of ccRCC patients with T3&4, T3, M1, G3&4, Stage III&IV, and Stage IV subgroups in LAMP1 high and low groups.

    Article Snippet: The human ccRCC cell lines A498 and 786-O were obtained from ATCC (Manassas, VA, USA).

    Techniques: Expressing

    FIGURE 4 A nomogram predicting 1 -, 3 -, and 5-year survival in ccRCC patients.

    Journal: Frontiers in immunology

    Article Title: Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.

    doi: 10.3389/fimmu.2024.1494005

    Figure Lengend Snippet: FIGURE 4 A nomogram predicting 1 -, 3 -, and 5-year survival in ccRCC patients.

    Article Snippet: The human ccRCC cell lines A498 and 786-O were obtained from ATCC (Manassas, VA, USA).

    Techniques:

    FIGURE 5 Kaplan-Meier survival analysis of the relationship between prognosis and different clinical variables in ccRCC patients. (A) Patients with low LAMP1 expression in cancer tissue had worse prognosis; (B-E) The higher the T and M stage, clinical stage and nuclear grade, the worse the prognosis.

    Journal: Frontiers in immunology

    Article Title: Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.

    doi: 10.3389/fimmu.2024.1494005

    Figure Lengend Snippet: FIGURE 5 Kaplan-Meier survival analysis of the relationship between prognosis and different clinical variables in ccRCC patients. (A) Patients with low LAMP1 expression in cancer tissue had worse prognosis; (B-E) The higher the T and M stage, clinical stage and nuclear grade, the worse the prognosis.

    Article Snippet: The human ccRCC cell lines A498 and 786-O were obtained from ATCC (Manassas, VA, USA).

    Techniques: Expressing

    FIGURE 6 (A) The protein detection results after overexpressing LAMP1 gene, knocking down LAMP1 gene, and knocking down LAMP1 gene on the basis of overexpression in 786-O and A498 cells. (B) The proliferation curves of 786-O and A498 cells (*P<0.05, **P<0.01, ***P<0.001). (C) The effects of LAMP1 overexpression and subsequent knockdown on the migration of 786-O and A498 cells in the wound healing assay. (D) The upregulation of LAMP1 levels significantly inhibits the migration and invasion of renal cancer cells in vitro. Transwell assay was performed to analyze the effects of upregulation and subsequent downregulation of LAMP1 levels on the migration and invasion of 786-O and A498 cells. (E) The effects of LAMP1 overexpression and subsequent knockdown on the colony formation of 786-O and A498 cells.

    Journal: Frontiers in immunology

    Article Title: Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.

    doi: 10.3389/fimmu.2024.1494005

    Figure Lengend Snippet: FIGURE 6 (A) The protein detection results after overexpressing LAMP1 gene, knocking down LAMP1 gene, and knocking down LAMP1 gene on the basis of overexpression in 786-O and A498 cells. (B) The proliferation curves of 786-O and A498 cells (*P<0.05, **P<0.01, ***P<0.001). (C) The effects of LAMP1 overexpression and subsequent knockdown on the migration of 786-O and A498 cells in the wound healing assay. (D) The upregulation of LAMP1 levels significantly inhibits the migration and invasion of renal cancer cells in vitro. Transwell assay was performed to analyze the effects of upregulation and subsequent downregulation of LAMP1 levels on the migration and invasion of 786-O and A498 cells. (E) The effects of LAMP1 overexpression and subsequent knockdown on the colony formation of 786-O and A498 cells.

    Article Snippet: The human ccRCC cell lines A498 and 786-O were obtained from ATCC (Manassas, VA, USA).

    Techniques: Over Expression, Knockdown, Migration, Wound Healing Assay, In Vitro, Transwell Assay